Dark under-eye circles – have we finally found a solution?

If you are concerned by dark circles and lines beneath the eyes, polynucleotides may be one option worth considering.

A tired or older-looking face in the mirror does not necessarily reflect how you really feel. Expensive eye creams and home remedies rarely offer a lasting solution, so more people are turning to science-based options. One promising active substance in aesthetic medicine is the polynucleotide. What is it, and how can it support rejuvenation of the under-eye area? Read on to discover how it may help create a fresher, more youthful appearance.

Why do creams have limited effects on dark circles and wrinkles?

Although eye creams are popular for dark circles and wrinkles, research suggests that their effect is often limited. A 2023 study found that commercial eye creams did not efficiently deliver active ingredients such as caffeine into the deeper layers of the skin, where they would need to act to produce certain results (ScienceDirect). A 2024 article also noted the limited scientific evidence for many creams in the eye area. This is why interest is growing in treatments that can influence skin structure, including polynucleotides. Book a consultation

Polynucleotides – have researchers found a treatment that works?

Polynucleotides were developed for medical use decades ago. They use purified DNA fragments generally obtained from natural sources such as salmon reproductive tissue. They were first used to support wound healing and anti-inflammatory processes, but researchers discovered that they could also stimulate fibroblasts, increase collagen production and improve skin structure. Following extensive laboratory and clinical research, they have become a valued option in aesthetic medicine.

How polynucleotides work for dark circles and under-eye lines

Polynucleotides can support the treatment of dark circles and under-eye lines by stimulating skin renewal and improving microcirculation. These naturally derived molecules increase collagen production, which can make the skin around the eyes denser.

Clinical research supports the use of polynucleotides in aesthetic medicine. Several studies have found that polynucleotide injections can reduce wrinkle depth and improve skin texture. Read more.

By supporting the skin in these ways, polynucleotides may reduce both dark shadows and fine lines and give the eye area a fresher appearance.

Can polynucleotides help with under-eye bags?

Under-eye bags can have several causes, including skin laxity, fluid retention or displaced fat. Polynucleotides strengthen skin structure and improve microcirculation, which may reduce puffiness and firm the area when bags are related to tired skin or fluid accumulation.

If the bags are caused by protruding fat pads, polynucleotides alone will not remove them. A surgical option such as lower-eyelid blepharoplasty may then be necessary.

Polynucleotides can nevertheless be used before and after surgery to support skin recovery and improve the final result.

How long do the results last, and are polynucleotides the best option for the under-eye area?

Visible changes can develop within a few weeks: the under-eye skin becomes smoother, better hydrated and less dark. A course of two to three sessions at four-week intervals is recommended for the best result. Results usually last six to nine months, depending on skin condition and lifestyle. Because polynucleotides improve the skin’s structure from within instead of temporarily filling it, they are considered one of the more natural options for dark circles and fine lines.

‘We have seen the effects of polynucleotides in our clients and clinic staff: the under-eye area looks fresher and the skin more even. The results have been visible and natural.’ – Agve Kask, founder of NOOR Clinic.

Can polynucleotides be combined with other eye-area treatments?

Yes. Polynucleotides combine well with other treatments for the eye area. Because they support deeper repair and cellular activity, they can be used before or after carboxytherapy, mesotherapy or eyelid surgery.

Combining methods can produce a natural yet noticeable result: less puffiness, darkness and wrinkling and more even, fresher-looking skin. Combinations are always based on an individual treatment plan prepared during the initial consultation. Book a consultation

How is a polynucleotide treatment performed?

1. Consultation and skin assessment
   Before treatment, we assess the skin’s condition and needs and create a plan for the selected area. We also take photographs for the treatment record.

2. Cleansing
   We carefully remove make-up, dirt and oil from the treatment area.

3. Application of numbing cream
   We apply numbing cream and allow it to work for 15–20 minutes.

4. Polynucleotide injections
   The solution is injected into the skin in small amounts using a specific technique and a very fine needle or cannula.

5. Brief skin reaction
   Small bumps, mild redness or injection marks may appear and generally subside within one to three days.

6. Home-care advice
   We provide instructions for caring for the area, such as avoiding make-up, saunas and vigorous rubbing for 24 hours.

If dark circles or fine lines beneath the eyes concern you, polynucleotide treatment may be worth considering. N8r.ee

If you would like advice or want to know whether it may suit you, please contact us. Contact us here